
Precision Isotope Enrichment for Next-Generation Nuclear Materials:
Bio‑Engineered Isotope Enrichment for a Clean Energy Future
At CurieBio we are redefining lithium isotope enrichment through advanced engineered solid media that delivers unmatched weight based precision, scalability, and environmental performance. Our solid-state enrichment platform selectively isolates lithium-6 with high efficiency while drastically reducing energy use, system complexity, and waste. This offers a cleaner, more modern alternative to current toxic chemical-exchange and laser based methods such as COLEX and AVLIS.
Why is Lithium Isotope Separation Important?
Lithium‑6 and Lithium‑7 are the backbone of next‑generation nuclear energy — Li‑6 enables tritium production for fusion, while Li‑7 stabilizes reactor coolant chemistry in advanced fission systems, making both isotopes essential to the future of clean, reliable power.
Problem and Need?
Current isotope separation technologies rely on large-scale infrastructure, toxic solvents, and multistage processes with high operational complexity.

These limitations restrict domestic production capacity, hinder distributed manufacturing, and pose environmental and safety challenges. There is a growing need for transformational separation technologies that are modular, low-energy, and scalable
LithoSphere: Nanoporous Sorbent Technology
LithoSphere is our breakthrough materials platform developed to bring molecular‑level precision to lithium isotope enrichment. Built on tunable, high‑surface‑area architectures, LithoSphere transforms enrichment from a legacy industrial process into a clean, scalable, next‑generation technology. By controlling interactions at the atomic scale, LithoSphere unlocks faster, cleaner, and more selective enrichment pathways — positioning it as a foundational technology for fusion, advanced reactors, and the future of clean energy.

The LithoSphere Advantage:
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Solid-state alternative to solvent-intensive chemical exchange
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Reduced energy intensity compared to thermal or electrochemical methods
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Modular, containerized deployment compatible with domestic supply chains
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Dual-use capability, integrating lithium purification and isotope enrichment on a single platform

Help Build the Future of Nuclear Innovation:
CurieBio is actively engaging strategic partners and investors to accelerate the commercial deployment of our LithoSphere technology. Our North Carolina–based team is dedicated to delivering advanced lithium‑enrichment materials that empower the future of fusion, next‑generation nuclear systems, and clean energy innovation — all while prioritizing sustainability, scalability, and U.S. energy resilience.
